ABSTRACT
Background: The pap smear is the screening test for the detection of premalignant lesion of the cervix. It should be done annually in all women of age 35 years and above. Pap smear screening of cervix can significantly reduce the deaths due to cervical carcinoma. Materials and methods: This was a prospective and descriptive study done for the period of 6 months from February 2018 to July 2018. A total of 158 women above the age of 21 years and married were included in the study. A Pap smear test was done after clinical examination in all women and sent to the department of Pathology of our tertiary care centre for cytopathological examination. Results: There were 150 cases with inflammatory smear, 2 cases of ASCUS, 3 cases of LSIL and 3 cases of HSIL. Women who were positive for ASCUS, LSIL and HSIL underwent colposcopy and guided biopsy. Most women with inflammatory smear were of age group 20-40 years, 2cases of ASCUS were of ages 35 years and 38 years, 3cases of LSIL were of age group 35-45 years and 3 cases of HSIL were of age group 45-55years. Conclusion: Thus cervical cancer is a preventable cancer if regular Pap smear screening test is done. It is simple, cost effective, non-invasive and easy to perform screening test for precancerous lesions of cervix.
ABSTRACT
Fine needle aspiration of thyroid lesions forms the first diagnostic tool in the preoperative evaluation of thyroid lesions. Thyroid diseases are important as these are curable with medical as well as surgical treatment. Enlargement of thyroid called as goiter is the most common manifestation of thyroid diseases. FNAC forms an important role to determine the nature of thyroid lesion whether benign or malignant. It is simple, safe, accurate and cost effective method. This was a prospective and descriptive study done for the period of 2 years from January 2016 to December 2017 in the Department of Pathology at our tertiary care hospital. A total of 100 patients with thyroid lesions came for FNAC, out of which 50 cases were received for histopathological correlation. There were 39 cases of benign thyroid lesions out of which multinodular goiter were the commonest. Papillary carcinoma was the most common malignant lesion amongst 11 cases. Benign lesions presented in younger age group (20-40 years) whereas malignant lesions had bimodal presentation (20-40 years and 40-60 years). Hereby I have analyzed different types of thyroid lesions in different age groups based on cytological evaluation followed by its histopathological confirmation.
ABSTRACT
Generally patients with breast tumors complain of lump in the breast which may be painful or painless and may be associated with nipple discharge or not. Benign tumors of the breast are common among younger age group <30 years. But the chances of malignancy increases with increasing age. Most of the cases of breast cancer are found in age group >50 years. FNAC forms the initial diagnostic method in patients with breast lump. A total of 250 patients with different breast lesions attended cytology section of our Pathology department for FNAC. Out of which 197 cases came for histopathological correlation in the study period of 2 years from January 2016 to December2017. Among these majority were benign tumors (114 cases) but an alarming number of 51cases were malignant. Next in number were benign breast diseases (24 cases). There was one case each of ductal papilloma, gynaecomastia. The commonest benign breast tumors were fibroadenoma whereas the commonest malignant tumors were infiltrating ductal carcinoma. There was one case each of lobular carcinoma in situ, infiltrating lobular carcinoma, medullary carcinoma, ductal carcinoma in male breast, inflammatory carcinoma, sarcoma breast. Hereby, we have analyzed different types of breast lesions in different age groups based on cytological evaluation followed by its histopathological confirmation.
ABSTRACT
Generally patients suffering from leukemia complain of very vague symptoms of low grade fever for 2-3 months, weight loss, loss of appetite, fatigue, recurrent infections, petechiae in the body. Thus high index of suspicion and proper diagnosis is needed. The patients who attend tertiary care centre with above symptoms should be initially diagnosed by doing complete blood count, peripheral blood smear examination followed by bone marrow aspiration and its examination. It provides high quality visualization of cell morphology and enables differential count. A total of 1793 patients attended Department of Pathology in the tertiary care centre for bone marrow examination. Of this majority of cases were diagnosed with erythroid hyperplasia with megaloblastic reaction. 152 cases were diagnosed with leukemias. There were 66 cases of ALL, 46 cases of AML, 35 cases of CML, 3 cases of CLL and 2 cases of CEL. Few cases of Multiple Myeloma, plasma cell dyscrasias and immune thrombocytopenic purpura were diagnosed. In this study, we have analysed the incidence of different types of leukemia in different age groups and their presenting sign and symptoms